Search results for "Roche Diagnostics"

showing 3 items of 3 documents

Performance Comparison of a Flow Cytometry-based and Two Commercial Chemiluminescent Immunoassays for Detection and Quantification of Antibodies Bind…

2021

ABSTRACTThe performance of a laboratory-developed quantitative IgG/IgA flow cytometry-based immunoassay (FCI) using Jurkat T cells stably expressing full-length native S protein was compared against Elecsys® electrochemiluminiscent (ECLIA) Anti-SARS-CoV-2 S (Roche Diagnostics, Pleasanton, CA, USA), and LIAISON® SARS-CoV-2 TrimericS IgG chemiluminiscent assay (CLIA) (Diasorin S.p.a, Saluggia, IT) for detection and quantitation of SARS-CoV-2-specific antibodies. A total of 225 serum/plasma specimens from 120 acute or convalescent COVID-19 individuals were included. Overall, IgG/IgA-FCI yielded the highest number of positives (n=179), followed by IgA-FCI (n=177), Roche ECLIA (n=175), IgG-FCI (…

medicine.diagnostic_testbiologyChemistrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Roche DiagnosticsMolecular biologyFlow cytometrylaw.inventionSerologyAntibody IsotypelawImmunoassaymedicinebiology.proteinAntibodyChemiluminescence
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Reference Values for a Homogeneous Ferritin Assay and Traceability to the 3rd International Recombinant Standard for Ferritin (NIBSC Code 94/572)

1999

Abstract Reference values for two ferritin assays (Tina-quant®a Ferritin, Enzymun®, both Roche Diagnostics, Mannheim, Germany) were established (136 males and 139 females). To rule out inflammation as well as iron deficiency in the reference population, subjects with the C-reactive protein concentration < 5 mg/l, and zinc protoporphyrin < 40 µmol/mol heme and the soluble transferrin receptor < 3 mg/l were selected. Taking into account latent iron deficiency as well as hereditary hemochromatosis the 5–95 percentile range was as follows: male, 27–365 μg/l; female, 13–148 μg/l for Tina-quant®a and 12–151 μg/l for Enzymun®. The Tinaquant® a Ferritin assay showed a very good correlation…

AdultMaleSerial dilutionClinical BiochemistryRoche Diagnosticslaw.inventionImmunoenzyme TechniquesReference ValueslawHumansReference populationbiologyBiochemistry (medical)Reproducibility of ResultsGeneral MedicineMiddle AgedAbbott DiagnosticsMolecular biologyFerritinHomogeneousReference valuesCalibrationFerritinsImmunologybiology.proteinRecombinant DNAFemalecclm
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Case Study: Internes Unternehmertum Roche Diagnostics Venturing

2003

Der Ruf nach Starkung der Innovationskraft und Freisetzung von Unternehmertum in Grosunternehmen ist schon seit geraumer Zeit zu vernehmen. Eine grose Popularitat gewann das Thema mit den Erkenntnissen von Peters und Waterman, die 1982 im Rahmen ihrer Analyse erfolgreicher, amerikanischer Unternehmen bereits auf die Resultate von Unternehmertum im Unternehmen hinwiesen.1 Darauf aufbauend entwickelte Pinchot sein Konzept des Intrapreneurings, das sich aus den Begriffen intracorporate und entrepreuring ableitet.2 Es folgten weitere Ansatze, denen im wesentlichen die zwei Oberziele Innovation und Vitalisierung des Unternehmens gemein sind.

Political scienceRoche DiagnosticsHumanities
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